Assembly and Dynamics of Myofibrils

We review some of the problems in determining how myofibrils may be assembled and just as importantly how this contractile structure may be renewed by sarcomeric proteins moving between the sarcomere and the cytoplasm. We also address in this personal review the recent evidence that indicates that t...

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Detalles Bibliográficos
Autores principales: Sanger, Joseph W., Wang, Jushuo, Fan, Yingli, White, Jennifer, Sanger, Jean M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896905/
https://www.ncbi.nlm.nih.gov/pubmed/20625425
http://dx.doi.org/10.1155/2010/858606
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author Sanger, Joseph W.
Wang, Jushuo
Fan, Yingli
White, Jennifer
Sanger, Jean M.
author_facet Sanger, Joseph W.
Wang, Jushuo
Fan, Yingli
White, Jennifer
Sanger, Jean M.
author_sort Sanger, Joseph W.
collection PubMed
description We review some of the problems in determining how myofibrils may be assembled and just as importantly how this contractile structure may be renewed by sarcomeric proteins moving between the sarcomere and the cytoplasm. We also address in this personal review the recent evidence that indicates that the assembly and dynamics of myofibrils are conserved whether the cells are analyzed in situ or in tissue culture conditions. We suggest that myofibrillogenesis is a fundamentally conserved process, comparable to protein synthesis, mitosis, or cytokinesis, whether examined in situ or in vitro.
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spelling pubmed-28969052010-07-12 Assembly and Dynamics of Myofibrils Sanger, Joseph W. Wang, Jushuo Fan, Yingli White, Jennifer Sanger, Jean M. J Biomed Biotechnol Review Article We review some of the problems in determining how myofibrils may be assembled and just as importantly how this contractile structure may be renewed by sarcomeric proteins moving between the sarcomere and the cytoplasm. We also address in this personal review the recent evidence that indicates that the assembly and dynamics of myofibrils are conserved whether the cells are analyzed in situ or in tissue culture conditions. We suggest that myofibrillogenesis is a fundamentally conserved process, comparable to protein synthesis, mitosis, or cytokinesis, whether examined in situ or in vitro. Hindawi Publishing Corporation 2010 2010-06-10 /pmc/articles/PMC2896905/ /pubmed/20625425 http://dx.doi.org/10.1155/2010/858606 Text en Copyright © 2010 Joseph W. Sanger et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sanger, Joseph W.
Wang, Jushuo
Fan, Yingli
White, Jennifer
Sanger, Jean M.
Assembly and Dynamics of Myofibrils
title Assembly and Dynamics of Myofibrils
title_full Assembly and Dynamics of Myofibrils
title_fullStr Assembly and Dynamics of Myofibrils
title_full_unstemmed Assembly and Dynamics of Myofibrils
title_short Assembly and Dynamics of Myofibrils
title_sort assembly and dynamics of myofibrils
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896905/
https://www.ncbi.nlm.nih.gov/pubmed/20625425
http://dx.doi.org/10.1155/2010/858606
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