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Effectiveness of strategies to increase the validity of findings from association studies: size vs. replication
BACKGROUND: The capacity of multiple comparisons to produce false positive findings in genetic association studies is abundantly clear. To address this issue, the concept of false positive report probability (FPRP) measures "the probability of no true association between a genetic variant and d...
Autores principales: | Weitkunat, Rolf, Kaelin, Etienne, Vuillaume, Grégory, Kallischnigg, Gerd |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896945/ https://www.ncbi.nlm.nih.gov/pubmed/20509879 http://dx.doi.org/10.1186/1471-2288-10-47 |
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