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Effectiveness of strategies to increase the validity of findings from association studies: size vs. replication

BACKGROUND: The capacity of multiple comparisons to produce false positive findings in genetic association studies is abundantly clear. To address this issue, the concept of false positive report probability (FPRP) measures "the probability of no true association between a genetic variant and d...

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Detalles Bibliográficos
Autores principales: Weitkunat, Rolf, Kaelin, Etienne, Vuillaume, Grégory, Kallischnigg, Gerd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896945/
https://www.ncbi.nlm.nih.gov/pubmed/20509879
http://dx.doi.org/10.1186/1471-2288-10-47

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