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The proline-rich peptide Bac7(1-35) reduces mortality from Salmonella typhimurium in a mouse model of infection

BACKGROUND: Bac7 is a proline-rich peptide with a potent in vitro antimicrobial activity against Gram-negative bacteria. Here we investigated its activity in biological fluids and in vivo using a mouse model of S. typhimurium infection. RESULTS: The efficacy of the active 1-35 fragment of Bac7 was a...

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Detalles Bibliográficos
Autores principales: Benincasa, Monica, Pelillo, Chiara, Zorzet, Sonia, Garrovo, Chiara, Biffi, Stefania, Gennaro, Renato, Scocchi, Marco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896951/
https://www.ncbi.nlm.nih.gov/pubmed/20573188
http://dx.doi.org/10.1186/1471-2180-10-178