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The proline-rich peptide Bac7(1-35) reduces mortality from Salmonella typhimurium in a mouse model of infection
BACKGROUND: Bac7 is a proline-rich peptide with a potent in vitro antimicrobial activity against Gram-negative bacteria. Here we investigated its activity in biological fluids and in vivo using a mouse model of S. typhimurium infection. RESULTS: The efficacy of the active 1-35 fragment of Bac7 was a...
Autores principales: | Benincasa, Monica, Pelillo, Chiara, Zorzet, Sonia, Garrovo, Chiara, Biffi, Stefania, Gennaro, Renato, Scocchi, Marco |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896951/ https://www.ncbi.nlm.nih.gov/pubmed/20573188 http://dx.doi.org/10.1186/1471-2180-10-178 |
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