HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction

Endoplasmic reticulum (ER) stress is a feature of secretory cells and of many diseases including cancer, neurodegeneration, and diabetes. Adaptation to ER stress depends on the activation of a signal transduction pathway known as the unfolded protein response (UPR). Enhanced expression of Hsp72 has...

Descripción completa

Detalles Bibliográficos
Autores principales: Gupta, Sanjeev, Deepti, Ayswaria, Deegan, Shane, Lisbona, Fernanda, Hetz, Claudio, Samali, Afshin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897763/
https://www.ncbi.nlm.nih.gov/pubmed/20625543
http://dx.doi.org/10.1371/journal.pbio.1000410

Ejemplares similares

Ejemplares similares