BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response

The unfolded protein response (UPR) is an intracellular signaling pathway that counteracts variable stresses that impair protein folding in the endoplasmic reticulum (ER). As such, the UPR is thought to be a homeostat that finely tunes ER protein folding capacity and ER abundance according to need....

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Detalles Bibliográficos
Autores principales: Pincus, David, Chevalier, Michael W., Aragón, Tomás, van Anken, Eelco, Vidal, Simon E., El-Samad, Hana, Walter, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897766/
https://www.ncbi.nlm.nih.gov/pubmed/20625545
http://dx.doi.org/10.1371/journal.pbio.1000415

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