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The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures
BACKGROUND: Stromal-epithelial interactions mediate breast development, and the initiation and progression of breast cancer. In the present study, we developed 3-dimensional (3D) in vitro models to study breast cancer tissue organization and the role of the microenvironment in phenotypic determinati...
Autores principales: | Krause, Silva, Maffini, Maricel V, Soto, Ana M, Sonnenschein, Carlos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897802/ https://www.ncbi.nlm.nih.gov/pubmed/20529269 http://dx.doi.org/10.1186/1471-2407-10-263 |
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