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Targeted Deletion of Kcne2 Causes Gastritis Cystica Profunda and Gastric Neoplasia
Gastric cancer is the second leading cause of cancer death worldwide. Predisposing factors include achlorhydria, Helicobacter pylori infection, oxyntic atrophy and TFF2-expressing metaplasia. In parietal cells, apical potassium channels comprising the KCNQ1 α subunit and the KCNE2 β subunit provide...
Autores principales: | Roepke, Torsten K., Purtell, Kerry, King, Elizabeth C., La Perle, Krista M. D., Lerner, Daniel J., Abbott, Geoffrey W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897890/ https://www.ncbi.nlm.nih.gov/pubmed/20625512 http://dx.doi.org/10.1371/journal.pone.0011451 |
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