Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops

Werner syndrome is an inherited human progeriod syndrome caused by mutations in the gene encoding the Werner Syndrome protein, WRN. It has both 3'-5' DNA helicase and exonuclease activities, and is suggested to have roles in many aspects of DNA metabolism, including DNA repair and telomere...

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Detalles Bibliográficos
Autores principales: Kusumoto-Matsuo, Rika, Opresko, Patricia L., Ramsden, Dale, Tahara, Hidetoshi, Bohr, Vilhelm A.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898018/
https://www.ncbi.nlm.nih.gov/pubmed/20519774

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