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Quality and quantity control of proteins in senescence
Autophagy has been implicated in aging and age-related diseases but its roles in these processes are far from straightforward: the anti-aging effect of autophagy has been shown in lower eukaryotes, and both pro- and anti-tumorigenic effects of autophagy have also been demonstrated. The new link betw...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898021/ https://www.ncbi.nlm.nih.gov/pubmed/20519777 |
| Sumario: | Autophagy has been implicated in aging and age-related diseases but its roles in these processes are far from straightforward: the anti-aging effect of autophagy has been shown in lower eukaryotes, and both pro- and anti-tumorigenic effects of autophagy have also been demonstrated. The new link between autophagy and senescence provides an insight into the diversified downstream effects of autophagy in various cellular contexts. |
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