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The Integrator Complex Recognizes a New Double Mark on the RNA Polymerase II Carboxyl-terminal Domain

The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (pol II) comprises multiple tandem repeats of the heptapeptide Tyr(1)-Ser(2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7). This unusual structure serves as a platform for the binding of factors required for expression of pol II-tra...

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Detalles Bibliográficos
Autores principales: Egloff, Sylvain, Szczepaniak, Sylwia Anna, Dienstbier, Martin, Taylor, Alice, Knight, Sophie, Murphy, Shona
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898319/
https://www.ncbi.nlm.nih.gov/pubmed/20457598
http://dx.doi.org/10.1074/jbc.M110.132530