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CR6-interacting Factor 1 (CRIF1) Regulates NF-E2-related Factor 2 (NRF2) Protein Stability by Proteasome-mediated Degradation

Free radicals generated by oxidative stress cause damage that can contribute to numerous chronic diseases. Mammalian cells respond to this damage by increased transcription of cytoprotective phase II genes, which are regulated by NRF2. Previously, it has been shown that NRF2 protein levels increase...

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Detalles Bibliográficos
Autores principales:	Kang, Hyo Jin, Hong, Young Bin, Kim, Hee Jeong, Bae, Insoo
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898415/ https://www.ncbi.nlm.nih.gov/pubmed/20427290 http://dx.doi.org/10.1074/jbc.M109.084590

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