Disruption of Lysosome Function Promotes Tumor Growth and Metastasis in Drosophila

Lysosome function is essential to many physiological processes. It has been suggested that deregulation of lysosome function could contribute to cancer. Through a genetic screen in Drosophila, we have discovered that mutations disrupting lysosomal degradation pathway components contribute to tumor d...

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Detalles Bibliográficos
Autores principales: Chi, Congwu, Zhu, Huanhu, Han, Min, Zhuang, Yuan, Wu, Xiaohui, Xu, Tian
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898421/
https://www.ncbi.nlm.nih.gov/pubmed/20418542
http://dx.doi.org/10.1074/jbc.M110.131714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898421/
https://www.ncbi.nlm.nih.gov/pubmed/20418542
http://dx.doi.org/10.1074/jbc.M110.131714

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