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Disruption of Lysosome Function Promotes Tumor Growth and Metastasis in Drosophila
Lysosome function is essential to many physiological processes. It has been suggested that deregulation of lysosome function could contribute to cancer. Through a genetic screen in Drosophila, we have discovered that mutations disrupting lysosomal degradation pathway components contribute to tumor d...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898421/ https://www.ncbi.nlm.nih.gov/pubmed/20418542 http://dx.doi.org/10.1074/jbc.M110.131714 |