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Interactions between Kar2p and Its Nucleotide Exchange Factors Sil1p and Lhs1p Are Mechanistically Distinct

Kar2p, an essential Hsp70 chaperone in the endoplasmic reticulum of Saccharomyces cerevisiae, facilitates the transport and folding of nascent polypeptides within the endoplasmic reticulum lumen. The chaperone activity of Kar2p is regulated by its intrinsic ATPase activity that can be stimulated by...

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Detalles Bibliográficos
Autores principales:	Hale, Sarah J., Lovell, Simon C., de Keyzer, Jeanine, Stirling, Colin J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898433/ https://www.ncbi.nlm.nih.gov/pubmed/20430899 http://dx.doi.org/10.1074/jbc.M110.111211

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