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Subunit and small-molecule interaction of ribonucleotide reductases via surface plasmon resonance biosensor analyses

Ribonucleotide reductase (RNR) synthesizes deoxyribonucleotides for DNA replication and repair and is controlled by sophisticated allosteric regulation involving differential affinity of nucleotides for regulatory sites. We have developed a robust and sensitive method for coupling biotinylated RNRs...

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Detalles Bibliográficos
Autores principales:	Crona, Mikael, Furrer, Ernst, Torrents, Eduard, Edgell, David R., Sjöberg, Britt-Marie
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898501/ https://www.ncbi.nlm.nih.gov/pubmed/20534631 http://dx.doi.org/10.1093/protein/gzq035

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