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Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.

Detalles Bibliográficos
Autores principales: Foley, David, Bailey, Patrick, Pieri, Myrtani, Meredith, David
Formato: Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898646/
https://www.ncbi.nlm.nih.gov/pubmed/19262922
http://dx.doi.org/10.1039/b818606e
Descripción
Sumario:Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.