Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.

Detalles Bibliográficos
Autores principales: Foley, David, Bailey, Patrick, Pieri, Myrtani, Meredith, David
Formato: Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2009
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898646/
https://www.ncbi.nlm.nih.gov/pubmed/19262922
http://dx.doi.org/10.1039/b818606e
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author Foley, David
Bailey, Patrick
Pieri, Myrtani
Meredith, David
author_facet Foley, David
Bailey, Patrick
Pieri, Myrtani
Meredith, David
author_sort Foley, David
collection PubMed
description Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.
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spelling pubmed-28986462011-09-26 Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1 Foley, David Bailey, Patrick Pieri, Myrtani Meredith, David Org Biomol Chem Chemistry Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro. Royal Society of Chemistry 2009-03-21 2009-01-21 /pmc/articles/PMC2898646/ /pubmed/19262922 http://dx.doi.org/10.1039/b818606e Text en This journal is © The Royal Society of Chemistry 2009 http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Foley, David
Bailey, Patrick
Pieri, Myrtani
Meredith, David
Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1
title Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1
title_full Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1
title_fullStr Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1
title_full_unstemmed Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1
title_short Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1
title_sort targeting ketone drugs towards transport by the intestinal peptide transporter, pept1
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898646/
https://www.ncbi.nlm.nih.gov/pubmed/19262922
http://dx.doi.org/10.1039/b818606e
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