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Use of silkworms for identification of drug candidates having appropriate pharmacokinetics from plant sources
BACKGROUND: We use silkworms to evaluate therapeutic effects of drug candidates. Our previous reports have revealed that there are common mechanisms of pharmacokinetics of chemicals in silkworms and mammals. In this report, we attempt to establish a method by using silkworms to identify chemicals fr...
Autores principales: | Asami, Yukihiro, Horie, Ryo, Hamamoto, Hiroshi, Sekimizu, Kazuhisa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898707/ https://www.ncbi.nlm.nih.gov/pubmed/20537191 http://dx.doi.org/10.1186/1471-2210-10-7 |
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