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Human Melanoma Initiating Cells Express Neural Crest Nerve Growth Factor Receptor CD271

The question whether tumorigenic cancer stem cells exist in human melanomas has arisen recently1. Here we show that in melanomas, tumor stem cells (MTSC) can be isolated prospectively as a highly enriched CD271+ MTSC population using a process that maximizes viable cell transplantation1,6. In this s...

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Detalles Bibliográficos
Autores principales: Boiko, Alexander D., Razorenova, Olga V., van de Rijn, Matt, Swetter, Susan M., Johnson, Denise L., Ly, Daphne P., Butler, Paris D., Yang, George P., Joshua, Benzion, Kaplan, Michael J., Longaker, Michael T., Weissman, Irving L.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898751/
https://www.ncbi.nlm.nih.gov/pubmed/20596026
http://dx.doi.org/10.1038/nature09161