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Chromatin regulation by Brg1 underlies heart muscle development and disease

Cardiac hypertrophy and failure are characterized by transcriptional reprogramming of gene expression. Adult cardiomyocytes in mice express primarily α-myosin heavy chain (α-MHC), whereas embryonic cardiomyocytes express β-MHC. Cardiac stress triggers adult hearts to undergo hypertrophy and a shift...

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Detalles Bibliográficos
Autores principales:	Hang, Calvin T., Yang, Jin, Han, Pei, Cheng, Hsiu-Ling, Shang, Ching, Ashley, Euan, Zhou, Bin, Chang, Ching-Pin
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898892/ https://www.ncbi.nlm.nih.gov/pubmed/20596014 http://dx.doi.org/10.1038/nature09130

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