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Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits
Impaired glucose tolerance (IGT) which precedes overt type 2 diabetes (T2DM) for decades is associated with multiple metabolic alterations in insulin sensitive tissues. In an UPLC-qTOF-mass spectrometry-driven non-targeted metabonomics approach we investigated plasma as well as spot urine of 51 non-...
Autores principales: | Zhao, Xinjie, Fritsche, Jens, Wang, Jiangshan, Chen, Jing, Rittig, Kilian, Schmitt-Kopplin, Philippe, Fritsche, Andreas, Häring, Hans-Ulrich, Schleicher, Erwin D., Xu, Guowang, Lehmann, Rainer |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899018/ https://www.ncbi.nlm.nih.gov/pubmed/20676218 http://dx.doi.org/10.1007/s11306-010-0203-1 |
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