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Interplay between Cdh1 and JNK activity during the cell cycle
The ubiquitin ligase APC/C(Cdh1) coordinates degradation of key cell cycle regulators. We report here that a nuclear-localized portion of the stress-activated kinase JNK is degraded by the APC/C(Cdh1) during exit from mitosis and G1 phase of the cell cycle. Expression of a non-degradable JNK induces...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899685/ https://www.ncbi.nlm.nih.gov/pubmed/20581839 http://dx.doi.org/10.1038/ncb2071 |