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The Microcirculation in Sepsis
SUMMARY: Sepsis is a leading cause of mortality in critically ill patients. The pathophysiology of sepsis involves a highly complex and integrated response, including the activation of various cell types, inflammatory mediators, and the haemostatic system. Recent evidence suggests an emerging role o...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900118/ https://www.ncbi.nlm.nih.gov/pubmed/20640135 |
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author | Tyagi, Asha Sethi, Ashok Kumar Girotra, Gautam Mohta, Medha |
author_facet | Tyagi, Asha Sethi, Ashok Kumar Girotra, Gautam Mohta, Medha |
author_sort | Tyagi, Asha |
collection | PubMed |
description | SUMMARY: Sepsis is a leading cause of mortality in critically ill patients. The pathophysiology of sepsis involves a highly complex and integrated response, including the activation of various cell types, inflammatory mediators, and the haemostatic system. Recent evidence suggests an emerging role of the microcirculation in sepsis, necessitating a shift in our locus away Irom the macrohaemodynamics to ill icrohaemodynanmics in a septic patient. This review article provides a brief overview of the microcirculation, its assessment techniques, and specific therapies to resuscitate the microhaemodynamics. |
format | Text |
id | pubmed-2900118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-29001182010-07-16 The Microcirculation in Sepsis Tyagi, Asha Sethi, Ashok Kumar Girotra, Gautam Mohta, Medha Indian J Anaesth Review Article SUMMARY: Sepsis is a leading cause of mortality in critically ill patients. The pathophysiology of sepsis involves a highly complex and integrated response, including the activation of various cell types, inflammatory mediators, and the haemostatic system. Recent evidence suggests an emerging role of the microcirculation in sepsis, necessitating a shift in our locus away Irom the macrohaemodynamics to ill icrohaemodynanmics in a septic patient. This review article provides a brief overview of the microcirculation, its assessment techniques, and specific therapies to resuscitate the microhaemodynamics. Medknow Publications 2009-06 /pmc/articles/PMC2900118/ /pubmed/20640135 Text en © Indian Journal of Anaesthesia http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Tyagi, Asha Sethi, Ashok Kumar Girotra, Gautam Mohta, Medha The Microcirculation in Sepsis |
title | The Microcirculation in Sepsis |
title_full | The Microcirculation in Sepsis |
title_fullStr | The Microcirculation in Sepsis |
title_full_unstemmed | The Microcirculation in Sepsis |
title_short | The Microcirculation in Sepsis |
title_sort | microcirculation in sepsis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900118/ https://www.ncbi.nlm.nih.gov/pubmed/20640135 |
work_keys_str_mv | AT tyagiasha themicrocirculationinsepsis AT sethiashokkumar themicrocirculationinsepsis AT girotragautam themicrocirculationinsepsis AT mohtamedha themicrocirculationinsepsis AT tyagiasha microcirculationinsepsis AT sethiashokkumar microcirculationinsepsis AT girotragautam microcirculationinsepsis AT mohtamedha microcirculationinsepsis |