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Activated Notch1 Target Genes during Embryonic Cell Differentiation Depend on the Cellular Context and Include Lineage Determinants and Inhibitors
BACKGROUND: Notch receptor signaling controls developmental cell fates in a cell-context dependent manner. Although Notch signaling directly regulates transcription via the RBP-J/CSL DNA binding protein, little is known about the target genes that are directly activated by Notch in the respective ti...
Autores principales: | Meier-Stiegen, Franziska, Schwanbeck, Ralf, Bernoth, Kristina, Martini, Simone, Hieronymus, Thomas, Ruau, David, Zenke, Martin, Just, Ursula |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900208/ https://www.ncbi.nlm.nih.gov/pubmed/20628604 http://dx.doi.org/10.1371/journal.pone.0011481 |
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