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Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known
BACKGROUND: The scope of this work is to show that the correct and complete definition of the system of muscle contraction requires the knowledge of both the mass and the acceleration of the load. RESULTS: The aim is achieved by making use of a model of muscle contraction that operates into two phas...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900230/ https://www.ncbi.nlm.nih.gov/pubmed/20565823 http://dx.doi.org/10.1186/1742-4682-7-24 |
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author | Grazi, Enrico Pozzati, Sara |
author_facet | Grazi, Enrico Pozzati, Sara |
author_sort | Grazi, Enrico |
collection | PubMed |
description | BACKGROUND: The scope of this work is to show that the correct and complete definition of the system of muscle contraction requires the knowledge of both the mass and the acceleration of the load. RESULTS: The aim is achieved by making use of a model of muscle contraction that operates into two phases. The first phase considers the effects of the power stroke in the absence of any hindrance. In the second phase viscous hindrance is introduced to match the experimental speed and yield of the contraction. It is shown that, at constant force of the load, changing load acceleration changes the time course of the pre-steady state of myofibril contraction. The decrease of the acceleration of the load from 9.8 m.s(-2 )to 1 m.s(-2 )increases the time length of the pre-steady state of the contraction from a few microseconds to many hundreds of microseconds and decreases the stiffness of the active fibre. CONCLUSIONS: We urge that in the study of muscle contraction both the mass and the acceleration of the load are specified. |
format | Text |
id | pubmed-2900230 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-29002302010-07-09 Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known Grazi, Enrico Pozzati, Sara Theor Biol Med Model Research BACKGROUND: The scope of this work is to show that the correct and complete definition of the system of muscle contraction requires the knowledge of both the mass and the acceleration of the load. RESULTS: The aim is achieved by making use of a model of muscle contraction that operates into two phases. The first phase considers the effects of the power stroke in the absence of any hindrance. In the second phase viscous hindrance is introduced to match the experimental speed and yield of the contraction. It is shown that, at constant force of the load, changing load acceleration changes the time course of the pre-steady state of myofibril contraction. The decrease of the acceleration of the load from 9.8 m.s(-2 )to 1 m.s(-2 )increases the time length of the pre-steady state of the contraction from a few microseconds to many hundreds of microseconds and decreases the stiffness of the active fibre. CONCLUSIONS: We urge that in the study of muscle contraction both the mass and the acceleration of the load are specified. BioMed Central 2010-06-18 /pmc/articles/PMC2900230/ /pubmed/20565823 http://dx.doi.org/10.1186/1742-4682-7-24 Text en Copyright ©2010 Grazi and Pozzati; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Grazi, Enrico Pozzati, Sara Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known |
title | Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known |
title_full | Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known |
title_fullStr | Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known |
title_full_unstemmed | Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known |
title_short | Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known |
title_sort | skeletal muscle contraction. the thorough definition of the contractile event requires both load acceleration and load mass to be known |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900230/ https://www.ncbi.nlm.nih.gov/pubmed/20565823 http://dx.doi.org/10.1186/1742-4682-7-24 |
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