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Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture

BACKGROUND: Neuronal transduction by adeno-associated viral (AAV) vectors has been demonstrated in cortex, brainstem, cerebellum, and sensory ganglia. Intrathecal delivery of AAV serotypes that transduce neurons in dorsal root ganglia (DRG) and spinal cord offers substantial opportunities to 1) furt...

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Detalles Bibliográficos
Autores principales:	Vulchanova, Lucy, Schuster, Daniel J, Belur, Lalitha R, Riedl, Maureen S, Podetz-Pedersen, Kelly M, Kitto, Kelley F, Wilcox, George L, McIvor, R Scott, Fairbanks, Carolyn A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900238/ https://www.ncbi.nlm.nih.gov/pubmed/20509925 http://dx.doi.org/10.1186/1744-8069-6-31

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