Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot”

We hypothesized that variants in genes expressed as a consequence of interactions between ovarian cancer cells and the host micro-environment could contribute to cancer susceptibility. We therefore used a two-stage approach to evaluate common single nucleotide polymorphisms (SNPs) in 173 genes invol...

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Detalles Bibliográficos
Autores principales: Johnatty, Sharon E., Beesley, Jonathan, Chen, Xiaoqing, Macgregor, Stuart, Duffy, David L., Spurdle, Amanda B., deFazio, Anna, Gava, Natalie, Webb, Penelope M., Rossing, Mary Anne, Doherty, Jennifer Anne, Goodman, Marc T., Lurie, Galina, Thompson, Pamela J., Wilkens, Lynne R., Ness, Roberta B., Moysich, Kirsten B., Chang-Claude, Jenny, Wang-Gohrke, Shan, Cramer, Daniel W., Terry, Kathryn L., Hankinson, Susan E., Tworoger, Shelley S., Garcia-Closas, Montserrat, Yang, Hannah, Lissowska, Jolanta, Chanock, Stephen J., Pharoah, Paul D., Song, Honglin, Whitemore, Alice S., Pearce, Celeste L., Stram, Daniel O., Wu, Anna H., Pike, Malcolm C., Gayther, Simon A., Ramus, Susan J., Menon, Usha, Gentry-Maharaj, Aleksandra, Anton-Culver, Hoda, Ziogas, Argyrios, Hogdall, Estrid, Kjaer, Susanne K., Hogdall, Claus, Berchuck, Andrew, Schildkraut, Joellen M., Iversen, Edwin S., Moorman, Patricia G., Phelan, Catherine M., Sellers, Thomas A., Cunningham, Julie M., Vierkant, Robert A., Rider, David N., Goode, Ellen L., Haviv, Izhak, Chenevix-Trench, Georgia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900295/
https://www.ncbi.nlm.nih.gov/pubmed/20628624
http://dx.doi.org/10.1371/journal.pgen.1001016

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