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A Forward-Genetic Screen and Dynamic Analysis of Lambda Phage Host-Dependencies Reveals an Extensive Interaction Network and a New Anti-Viral Strategy

Latently infecting viruses are an important class of virus that plays a key role in viral evolution and human health. Here we report a genome-scale forward-genetics screen for host-dependencies of the latently-infecting bacteriophage lambda. This screen identified 57 Escherichia coli (E. coli) genes...

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Detalles Bibliográficos
Autores principales:	Maynard, Nathaniel D., Birch, Elsa W., Sanghvi, Jayodita C., Chen, Lu, Gutschow, Miriam V., Covert, Markus W.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900299/ https://www.ncbi.nlm.nih.gov/pubmed/20628568 http://dx.doi.org/10.1371/journal.pgen.1001017

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