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Extensive DNA End Processing by Exo1 and Sgs1 Inhibits Break-Induced Replication

Homology-dependent repair of DNA double-strand breaks (DSBs) by gene conversion involves short tracts of DNA synthesis and limited loss of heterozygosity (LOH). For DSBs that present only one end, repair occurs by invasion into a homologous sequence followed by replication to the end of the chromoso...

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Detalles Bibliográficos
Autores principales: Marrero, Vanessa A., Symington, Lorraine S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900301/
https://www.ncbi.nlm.nih.gov/pubmed/20628570
http://dx.doi.org/10.1371/journal.pgen.1001007