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Extensive DNA End Processing by Exo1 and Sgs1 Inhibits Break-Induced Replication
Homology-dependent repair of DNA double-strand breaks (DSBs) by gene conversion involves short tracts of DNA synthesis and limited loss of heterozygosity (LOH). For DSBs that present only one end, repair occurs by invasion into a homologous sequence followed by replication to the end of the chromoso...
Autores principales: | Marrero, Vanessa A., Symington, Lorraine S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900301/ https://www.ncbi.nlm.nih.gov/pubmed/20628570 http://dx.doi.org/10.1371/journal.pgen.1001007 |
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