Id4, a New Candidate Gene for Senile Osteoporosis, Acts as a Molecular Switch Promoting Osteoblast Differentiation

Excessive accumulation of bone marrow adipocytes observed in senile osteoporosis or age-related osteopenia is caused by the unbalanced differentiation of MSCs into bone marrow adipocytes or osteoblasts. Several transcription factors are known to regulate the balance between adipocyte and osteoblast...

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Detalles Bibliográficos
Autores principales: Tokuzawa, Yoshimi, Yagi, Ken, Yamashita, Yzumi, Nakachi, Yutaka, Nikaido, Itoshi, Bono, Hidemasa, Ninomiya, Yuichi, Kanesaki-Yatsuka, Yukiko, Akita, Masumi, Motegi, Hiromi, Wakana, Shigeharu, Noda, Tetsuo, Sablitzky, Fred, Arai, Shigeki, Kurokawa, Riki, Fukuda, Toru, Katagiri, Takenobu, Schönbach, Christian, Suda, Tatsuo, Mizuno, Yosuke, Okazaki, Yasushi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900302/
https://www.ncbi.nlm.nih.gov/pubmed/20628571
http://dx.doi.org/10.1371/journal.pgen.1001019

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