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PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
In order to proliferate and expand in an environment with limited nutrients, cancer cells co-opt cellular regulatory pathways that facilitate adaptation and thereby maintain tumor growth and survival potential. The endoplasmic reticulum (ER) is uniquely positioned to sense nutrient deprivation stres...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900533/ https://www.ncbi.nlm.nih.gov/pubmed/20453876 http://dx.doi.org/10.1038/onc.2010.153 |