Allelic polymorphism in the T cell receptor and its impact on immune responses

In comparison to human leukocyte antigen (HLA) polymorphism, the impact of allelic sequence variation within T cell receptor (TCR) loci is much less understood. Particular TCR loci have been associated with autoimmunity, but the molecular basis for this phenomenon is undefined. We examined the T cel...

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Detalles Bibliográficos
Autores principales: Gras, Stephanie, Chen, Zhenjun, Miles, John J., Liu, Yu Chih, Bell, Melissa J., Sullivan, Lucy C., Kjer-Nielsen, Lars, Brennan, Rebekah M., Burrows, Jacqueline M., Neller, Michelle A., Khanna, Rajiv, Purcell, Anthony W., Brooks, Andrew G., McCluskey, James, Rossjohn, Jamie, Burrows, Scott R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901058/
https://www.ncbi.nlm.nih.gov/pubmed/20566715
http://dx.doi.org/10.1084/jem.20100603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901058/
https://www.ncbi.nlm.nih.gov/pubmed/20566715
http://dx.doi.org/10.1084/jem.20100603

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