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Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics

The sphingosine 1-phosphate receptor 1 (S1P(1)) promotes lymphocyte egress from lymphoid organs. Previous work showed that agonist-induced internalization of this G protein–coupled receptor correlates with inhibition of lymphocyte egress and results in lymphopenia. However, it is unclear if S1P(1) i...

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Detalles Bibliográficos
Autores principales:	Thangada, Shobha, Khanna, Kamal M., Blaho, Victoria A., Oo, Myat Lin, Im, Dong-Soon, Guo, Caiying, Lefrancois, Leo, Hla, Timothy
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901064/ https://www.ncbi.nlm.nih.gov/pubmed/20584883 http://dx.doi.org/10.1084/jem.20091343

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