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The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis
A recessive mutation named Justy was found that abolishes B lymphopoiesis but does not impair other major aspects of hematopoiesis. Transplantation experiments showed that homozygosity for Justy prevented hematopoietic progenitors from generating B cells but did not affect the ability of bone marrow...
Autores principales: | Lu, Ping, Hankel, Isaiah L., Knisz, Judit, Marquardt, Andreas, Chiang, Ming-Yi, Grosse, Johannes, Constien, Rainer, Meyer, Thomas, Schroeder, Andreas, Zeitlmann, Lutz, Al-Alem, Umaima, Friedman, Ann D., Elliott, Eric I., Meyerholz, David K., Waldschmidt, Thomas J., Rothman, Paul B., Colgan, John D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901076/ https://www.ncbi.nlm.nih.gov/pubmed/20530203 http://dx.doi.org/10.1084/jem.20100147 |
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