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Abnormal Excitability of Oblique Dendrites Implicated in Early Alzheimer's: A Computational Study

The integrative properties of cortical pyramidal dendrites are essential to the neural basis of cognitive function, but the impact of amyloid beta protein (aβ) on these properties in early Alzheimer's is poorly understood. In animal models, electrophysiological studies of proximal dendrites hav...

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Detalles Bibliográficos
Autores principales: Morse, Thomas M., Carnevale, Nicholas T., Mutalik, Pradeep G., Migliore, Michele, Shepherd, Gordon M.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901152/
https://www.ncbi.nlm.nih.gov/pubmed/20725509
http://dx.doi.org/10.3389/fncir.2010.00016