DNA breakage and cell cycle checkpoint abrogation induced by a therapeutic thiopurine and UVA radiation

The frequency of squamous cell skin carcinoma in organ transplant patients is around 100-fold higher than normal. This dramatic example of therapy-related cancer reflects exposure to sunlight and to immunosuppressive drugs. Here we demonstrate that the interaction between low doses of UVA, the major...

Descripción completa

Detalles Bibliográficos
Autores principales: Brem, Reto, Li, Feng, Montaner, Beatriz, Reelfs, Olivier, Karran, Peter
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901207/
https://www.ncbi.nlm.nih.gov/pubmed/20440263
http://dx.doi.org/10.1038/onc.2010.140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901207/
https://www.ncbi.nlm.nih.gov/pubmed/20440263
http://dx.doi.org/10.1038/onc.2010.140

Ejemplares similares