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DNA breakage and cell cycle checkpoint abrogation induced by a therapeutic thiopurine and UVA radiation
The frequency of squamous cell skin carcinoma in organ transplant patients is around 100-fold higher than normal. This dramatic example of therapy-related cancer reflects exposure to sunlight and to immunosuppressive drugs. Here we demonstrate that the interaction between low doses of UVA, the major...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901207/ https://www.ncbi.nlm.nih.gov/pubmed/20440263 http://dx.doi.org/10.1038/onc.2010.140 |