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Naturally occurring variations in sequence length creates microRNA isoforms that differ in argonaute effector complex specificity

BACKGROUND: Micro(mi)RNAs are short RNA sequences, ranging from 16 to 35 nucleotides (miRBase; http://www.mirbase.org). The majority of the identified sequences are 21 or 22 nucleotides in length. Despite the range of sequence lengths for different miRNAs, individual miRNAs were thought to have a sp...

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Detalles Bibliográficos
Autores principales: Ebhardt, H Alexander, Fedynak, Amber, Fahlman, Richard P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901367/
https://www.ncbi.nlm.nih.gov/pubmed/20534119
http://dx.doi.org/10.1186/1758-907X-1-12