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Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations
Background. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901602/ https://www.ncbi.nlm.nih.gov/pubmed/20631826 http://dx.doi.org/10.4061/2010/143679 |
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author | Golukhova, Elena Z. Polunina, Anna G. Zhuravleva, Svetlana V. Lefterova, Natalia P. Begachev, Alexey V. |
author_facet | Golukhova, Elena Z. Polunina, Anna G. Zhuravleva, Svetlana V. Lefterova, Natalia P. Begachev, Alexey V. |
author_sort | Golukhova, Elena Z. |
collection | PubMed |
description | Background. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in the study. Echocardiography was performed in 2-3 days before surgery. A transcranial Doppler system was used for registering intraoperative microemboli. Results. Preoperative left atrium and left ventricular end-systolic and end-diastolic sizes significantly correlated with intraoperative microembolic load (rs = 0.48, 0.57 and 0.53, Ps < .01, resp.). The associations between left ventricular diameters and number of cerebral microemboli remained significant when cardiopulmonary bypass time was included as a covariate into the analysis. Conclusions. The present results demonstrate that increased size of left heart chambers is an influential risk factor for elevated cerebral microembolic load during open heart operations. Mini-invasive surgery and carbon dioxide insufflation into wound cavity may be considered as neuroprotective approaches in patients with high risk of cerebral microembolism. |
format | Text |
id | pubmed-2901602 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-29016022010-07-14 Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations Golukhova, Elena Z. Polunina, Anna G. Zhuravleva, Svetlana V. Lefterova, Natalia P. Begachev, Alexey V. Cardiol Res Pract Research Article Background. Microemboli are a widely recognized etiological factor of cerebral complications in cardiac surgery patients. The present study was aimed to determine if size of left cardiac chambers relates to cerebral microembolic load in open heart operations. Methods. Thirty patients participated in the study. Echocardiography was performed in 2-3 days before surgery. A transcranial Doppler system was used for registering intraoperative microemboli. Results. Preoperative left atrium and left ventricular end-systolic and end-diastolic sizes significantly correlated with intraoperative microembolic load (rs = 0.48, 0.57 and 0.53, Ps < .01, resp.). The associations between left ventricular diameters and number of cerebral microemboli remained significant when cardiopulmonary bypass time was included as a covariate into the analysis. Conclusions. The present results demonstrate that increased size of left heart chambers is an influential risk factor for elevated cerebral microembolic load during open heart operations. Mini-invasive surgery and carbon dioxide insufflation into wound cavity may be considered as neuroprotective approaches in patients with high risk of cerebral microembolism. SAGE-Hindawi Access to Research 2010-06-13 /pmc/articles/PMC2901602/ /pubmed/20631826 http://dx.doi.org/10.4061/2010/143679 Text en Copyright © 2010 Elena Z. Golukhova et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Golukhova, Elena Z. Polunina, Anna G. Zhuravleva, Svetlana V. Lefterova, Natalia P. Begachev, Alexey V. Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
title | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
title_full | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
title_fullStr | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
title_full_unstemmed | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
title_short | Size of Left Cardiac Chambers Correlates with Cerebral Microembolic Load in Open Heart Operations |
title_sort | size of left cardiac chambers correlates with cerebral microembolic load in open heart operations |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901602/ https://www.ncbi.nlm.nih.gov/pubmed/20631826 http://dx.doi.org/10.4061/2010/143679 |
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