Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp

In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolite...

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Autores principales: Vairappan, Charles Santhanaraju, Ishii, Takahiro, Lee, Tan Kai, Suzuki, Minoru, Zhaoqi, Zhan
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901821/
https://www.ncbi.nlm.nih.gov/pubmed/20631866
http://dx.doi.org/10.3390/md8061743
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author Vairappan, Charles Santhanaraju
Ishii, Takahiro
Lee, Tan Kai
Suzuki, Minoru
Zhaoqi, Zhan
author_facet Vairappan, Charles Santhanaraju
Ishii, Takahiro
Lee, Tan Kai
Suzuki, Minoru
Zhaoqi, Zhan
author_sort Vairappan, Charles Santhanaraju
collection PubMed
description In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolites, aplysidiol (2), cupalaurenol (3), 1-methyl-2,3,5-tribromoindole (4), and chamigrane epoxide (5), were isolated and identified. Isolated metabolites exhibited potent antibacterial activities against clinical bacteria, Staphylococcus aureus, Staphylococcus sp., Streptococcus pyogenes, Salmonella sp. and Vibrio cholerae.
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spelling pubmed-29018212010-07-14 Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp Vairappan, Charles Santhanaraju Ishii, Takahiro Lee, Tan Kai Suzuki, Minoru Zhaoqi, Zhan Mar Drugs Article In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolites, aplysidiol (2), cupalaurenol (3), 1-methyl-2,3,5-tribromoindole (4), and chamigrane epoxide (5), were isolated and identified. Isolated metabolites exhibited potent antibacterial activities against clinical bacteria, Staphylococcus aureus, Staphylococcus sp., Streptococcus pyogenes, Salmonella sp. and Vibrio cholerae. Molecular Diversity Preservation International 2010-05-26 /pmc/articles/PMC2901821/ /pubmed/20631866 http://dx.doi.org/10.3390/md8061743 Text en © 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Vairappan, Charles Santhanaraju
Ishii, Takahiro
Lee, Tan Kai
Suzuki, Minoru
Zhaoqi, Zhan
Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp
title Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp
title_full Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp
title_fullStr Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp
title_full_unstemmed Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp
title_short Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp
title_sort antibacterial activities of a new brominated diterpene from borneon laurencia spp
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901821/
https://www.ncbi.nlm.nih.gov/pubmed/20631866
http://dx.doi.org/10.3390/md8061743
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AT leetankai antibacterialactivitiesofanewbrominatedditerpenefromborneonlaurenciaspp
AT suzukiminoru antibacterialactivitiesofanewbrominatedditerpenefromborneonlaurenciaspp
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