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Aldo-Keto Reductases in the Eye
Aldose reductase (AKR1B1) is an NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Accelerated glucose metabolism through this pathway has been implicated in diabetic cataract and retinopathy. Some human tissues contain AKR1B1 as well as AKR1B10, a clos...
Autores principales: | Huang, Shun Ping, Palla, Suryanarayana, Ruzycki, Philip, Varma, Ross Arjun, Harter, Theresa, Reddy, G. Bhanuprakesh, Petrash, J. Mark |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902055/ https://www.ncbi.nlm.nih.gov/pubmed/20628518 http://dx.doi.org/10.1155/2010/521204 |
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