Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports

Two young male patients treated seven and four years back, for malignant glioma, returned with recurrence at the same site, with a World Health Organization (WHO) Performance Score of four and two. Both underwent resurgery and received postoperative reirradiation of 5040 cGy in 28 fractions and conc...

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Autores principales: TR, Arulponni, MG, Janaki, S, Nirmala
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902119/
https://www.ncbi.nlm.nih.gov/pubmed/20668597
http://dx.doi.org/10.4103/0973-1075.58464
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author TR, Arulponni
MG, Janaki
S, Nirmala
author_facet TR, Arulponni
MG, Janaki
S, Nirmala
author_sort TR, Arulponni
collection PubMed
description Two young male patients treated seven and four years back, for malignant glioma, returned with recurrence at the same site, with a World Health Organization (WHO) Performance Score of four and two. Both underwent resurgery and received postoperative reirradiation of 5040 cGy in 28 fractions and concurrent Temozolomide 75 mg/m(2) body surface area (BSA) daily, and one patient received additional adjuvant Temozolomide 250 mg (150 mg/m(2) BSA). Both patients tolerated the treatment well with 16 and 14 months follow-up from the time of recurrence. They were symptom-free, with normal physical function and good mental state, and resumed their respective jobs.
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spelling pubmed-29021192010-07-28 Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports TR, Arulponni MG, Janaki S, Nirmala Indian J Palliat Care Case Report Two young male patients treated seven and four years back, for malignant glioma, returned with recurrence at the same site, with a World Health Organization (WHO) Performance Score of four and two. Both underwent resurgery and received postoperative reirradiation of 5040 cGy in 28 fractions and concurrent Temozolomide 75 mg/m(2) body surface area (BSA) daily, and one patient received additional adjuvant Temozolomide 250 mg (150 mg/m(2) BSA). Both patients tolerated the treatment well with 16 and 14 months follow-up from the time of recurrence. They were symptom-free, with normal physical function and good mental state, and resumed their respective jobs. Medknow Publications 2009 /pmc/articles/PMC2902119/ /pubmed/20668597 http://dx.doi.org/10.4103/0973-1075.58464 Text en © Indian Journal of Palliative Care http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
TR, Arulponni
MG, Janaki
S, Nirmala
Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports
title Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports
title_full Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports
title_fullStr Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports
title_full_unstemmed Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports
title_short Palliative Benefits of the Multimodality Approach in the Re-treatment of Recurrent Malignant Glioma: Two Case Reports
title_sort palliative benefits of the multimodality approach in the re-treatment of recurrent malignant glioma: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902119/
https://www.ncbi.nlm.nih.gov/pubmed/20668597
http://dx.doi.org/10.4103/0973-1075.58464
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AT mgjanaki palliativebenefitsofthemultimodalityapproachintheretreatmentofrecurrentmalignantgliomatwocasereports
AT snirmala palliativebenefitsofthemultimodalityapproachintheretreatmentofrecurrentmalignantgliomatwocasereports

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