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Synthetic Peptides as Structural Maquettes of Angiotensin-I Converting Enzyme Catalytic Sites
The rational design of synthetic peptides is proposed as an efficient strategy for the structural investigation of crucial protein domains difficult to be produced. Only after half a century since the function of ACE was first reported, was its crystal structure solved. The main obstacle to be overc...
Autores principales: | Spyranti, Zinovia, Galanis, Athanassios S., Pairas, George, Spyroulias, Georgios A., Manessi-Zoupa, Evy, Cordopatis, Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902127/ https://www.ncbi.nlm.nih.gov/pubmed/20634989 http://dx.doi.org/10.1155/2010/820476 |
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