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The role of noise and positive feedback in the onset of autosomal dominant diseases

BACKGROUND: Autosomal dominant (AD) diseases result when a single mutant or non-functioning gene is present on an autosomal chromosome. These diseases often do not emerge at birth. There are presently two prevailing theories explaining the expression of AD diseases. One explanation originates from t...

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Detalles Bibliográficos
Autores principales: Bosl, William J, Li, Rong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902440/
https://www.ncbi.nlm.nih.gov/pubmed/20587063
http://dx.doi.org/10.1186/1752-0509-4-93

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