Induction of cytotoxic T lymphocytes primed with Tumor RNA-loaded Dendritic Cells in esophageal squamous cell carcinoma: preliminary step for DC vaccine design

BACKGROUND: Dendritic Cells (DC) are potent antigen presenting cells with the ability to prime naïve T cells and convert them to cytotoxic T-lymphocytes (CTL). We evaluated the capability of autologous DCs transfected with total tumor and normal RNA to induce cytotoxic CTL as the preliminary step to...

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Detalles Bibliográficos
Autores principales: Gholamin, Mehran, Moaven, Omeed, Farshchian, Moein, Mahmoudi, Mahmoud, Sankian, Mojtaba, Memar, Bahram, Forghani, Mohammad Naser, Malekzadeh, Reza, Rajabi-Mashhadi, Mohammad Taghi, Abbaszadegan, Mohammad Reza
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902443/
https://www.ncbi.nlm.nih.gov/pubmed/20525404
http://dx.doi.org/10.1186/1471-2407-10-261

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