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Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases
BACKGROUND: Blockade of the angiotensin (ANG) II type 1 receptor (AT1R) inhibits tumour growth in several cancers, including colorectal cancer (CRC) liver metastases. While AT1R blockade has been extensively studied, the potential of targeting the antagonistically acting AT2R in cancer has not been...
Autores principales: | Ager, Eleanor I, Chong, Way W, Wen, Shu-wen, Christophi, Christopher |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902462/ https://www.ncbi.nlm.nih.gov/pubmed/20584290 http://dx.doi.org/10.1186/1475-2867-10-19 |
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