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Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases

BACKGROUND: Blockade of the angiotensin (ANG) II type 1 receptor (AT1R) inhibits tumour growth in several cancers, including colorectal cancer (CRC) liver metastases. While AT1R blockade has been extensively studied, the potential of targeting the antagonistically acting AT2R in cancer has not been...

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Detalles Bibliográficos
Autores principales: Ager, Eleanor I, Chong, Way W, Wen, Shu-wen, Christophi, Christopher
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902462/
https://www.ncbi.nlm.nih.gov/pubmed/20584290
http://dx.doi.org/10.1186/1475-2867-10-19

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