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Geranylgeranyltransferase I is essential for dendritic development of cerebellar Purkinje cells
BACKGROUND: During cerebellar development, Purkinje cells (PCs) form the most elaborate dendritic trees among neurons in the brain, but the mechanism regulating PC arborization remains largely unknown. Geranylgeranyltransferase I (GGT) is a prenyltransferase that is responsible for lipid modificatio...
Autores principales: | Wu, Kong-Yan, Zhou, Xiu-Ping, Luo, Zhen-Ge |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902468/ https://www.ncbi.nlm.nih.gov/pubmed/20540740 http://dx.doi.org/10.1186/1756-6606-3-18 |
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