Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells

BACKGROUND: Cytoplasmic lipid-droplets are common inclusions of eukaryotic cells. Lipid-droplet binding thalidomide analogs (2,6-dialkylphenyl-4/5-amino-substituted-5,6,7-trifluorophthalimides) with potent anticancer activities were synthesized. RESULTS: Cytotoxicity was detected in different cell l...

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Detalles Bibliográficos
Autores principales: Puskás, László G, Fehér, Liliána Z, Vizler, Csaba, Ayaydin, Ferhan, Rásó, Erzsébet, Molnár, Eszter, Magyary, István, Kanizsai, Iván, Gyuris, Márió, Madácsi, Ramóna, Fábián, Gabriella, Farkas, Klaudia, Hegyi, Péter, Baska, Ferenc, Ózsvári, Béla, Kitajka, Klára
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902471/
https://www.ncbi.nlm.nih.gov/pubmed/20525221
http://dx.doi.org/10.1186/1476-511X-9-56

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